An African-American woman becomes an unwitting pioneer for medical breakthroughs when her cells are used to create the first immortal human cell line in the early 1950s. Rose Byrne, Renée Elise Goldsberry, Oprah Winfrey, Ninja N. Devoe, Lisa Arrindell, Earl Poitier, L. Warren Young Added on HBO 2023-06-27, leaving 2024-03-31. Youtube Trailer

A platonic pair of former best friends approaching midlife reconnect after a long rift. The duo’s friendship becomes more consuming—and destabilizes their lives in a hilarious way. Rose Byrne, Seth Rogen, Luke Macfarlane, Tre Hale, Andrew Lopez, Carla Gallo, Alisha Wainwright Added on Apple 2023-05-04.

Annie is stuck in a long-term relationship with Duncan – an obsessive fan of obscure rocker Tucker Crowe. When the acoustic demo of Tucker's hit record from 25 years ago surfaces, its discovery leads to a life-changing encounter with the … Rose Byrne, Ethan Hawke, Chris O'Dowd, Azhy Robertson, Lily Brazier, Megan Dodds, Ayoola Smart Added on Amazon Prime 2023-02-04. Youtube Trailer

Sheila Rubin is a quietly tormented housewife in ’80s San Diego. Behind closed doors, she battles extreme personal demons and a vicious inner voice. But things change when she discovers aerobics, sparking a journey toward empowerment and success. Rose Byrne, Rory Scovel, Dierdre Friel, Della Saba, Lou Taylor Pucci, Paul Sparks, Ashley Liao Added on Apple 2022-05-30. Youtube Trailer

A baby pufferfish travels through a wondrous microworld full of fantastical creatures as he searches for a home on the Great Barrier Reef. Rose Byrne, Added on Netflix 2021-12-16. Youtube Trailer

With a new iPhone, an apartment near the Grove, and a comfortable bank account left to her by her beloved late husband, Marnie Minervini has happily relocated from New Jersey to Los Angeles to be near her daughter Lori, a … Susan Sarandon, Rose Byrne, J.K. Simmons, Cecily Strong, Jerrod Carmichael, Michael McKean, Jason Ritter Added on Starz 2024-02-01. Youtube Trailer

After a quick courtship, two lovers hastily decide to tie the knot. As their first year of marriage unfolds, temptation and incompatibility put their relationship in jeopardy. Rafe Spall, Rose Byrne, Anna Faris, Jason Flemyng, Stephen Merchant, Minnie Driver, Olivia Colman Added on HBO 2023-02-05. Added on Amazon Prime 2023-10-30. Youtube Trailer

Matthew, a young advertising executive in Chicago, puts his life and a business trip to China on hold when he thinks he sees Lisa, the love of his life who left him without a word two years earlier, walking out … Josh Hartnett, Rose Byrne, Matthew Lillard, Diane Kruger, Christopher Cousins, Jessica Paré, Vlasta Vrana Added on HBO 2022-12-19. Added on Amazon Prime 2023-07-26. Youtube Trailer

A love story set in 1930s England that follows 17-year-old Cassandra Mortmain, and the fortunes of her eccentric family, struggling to survive in a decaying English castle. Based on Dodie Smith's 1948 novel with the same name. Romola Garai, Rose Byrne, Tara Fitzgerald, Bill Nighy, Henry Thomas, Henry Cavill, Marc Blucas Added on Amazon Prime 2021-11-06. Added on Starz 2023-02-10.

A teacher opens a time capsule that has been dug up at his son's elementary school; in it are some chilling predictions -- some that have already occurred and others that are about to -- that lead him to believe … Nicolas Cage, Rose Byrne, Chandler Canterbury, Ben Mendelsohn, Nadia Townsend, Terry Camilleri, Lara Robinson Added on Amazon Prime 2023-02-06. Youtube Trailer

A young, hipster entrepreneur crashes and burns on the eve of his company’s big launch. With his entire life in disarray, he leaves Manhattan to move in with his estranged pregnant sister, brother-in-law and three year-old nephew in the suburbs … Nick Kroll, Rose Byrne, Bobby Cannavale, Joel McHale, Caitlin FitzGerald, Bobby Moynihan, Josh Charles Added on Starz 2023-01-18. Youtube Trailer

The inhabitants of the British Isles have lost their battle against the onslaught of disease, as the deadly rage virus has killed every citizen there. Six months later, a group of Americans dare to set foot on the isles, convinced … Robert Carlyle, Rose Byrne, Jeremy Renner, Harold Perrineau, Catherine McCormack, Imogen Poots, Mackintosh Muggleton Added on HBO 2022-12-28. Youtube Trailer

When Pete and Ellie decide to start a family, they stumble into the world of foster care adoption. They hope to take in one small child but when they meet three siblings, including a rebellious 15 year old girl, they … Mark Wahlberg, Rose Byrne, Allyn Rachel, Isabela Merced, Julie Hagerty, Tig Notaro, Octavia Spencer Added on Paramount 2022-05-14. Youtube Trailer

A teenage girl is raised underground by a robot "Mother", designed to repopulate the earth following an extinction event. But their unique bond is threatened when an inexplicable stranger arrives with alarming news. Clara Rugaard, Rose Byrne, Hilary Swank, Luke Hawker, Tahlia Sturzaker, Maddie Lenton, Hazel Sandery Added on Netflix 2022-03-29. Youtube Trailer

The true story of the movement to ratify the Equal Rights Amendment, and the unexpected backlash led by a conservative woman named Phyllis Schlafly, aka “the sweetheart of the silent majority.” Cate Blanchett, Rose Byrne, Uzo Aduba, Margo Martindale, Tracey Ullman, Elizabeth Banks, Sarah Paulson Added on Hulu 2022-03-29. Youtube Trailer

Damages is an American legal thriller television series created by the writing and production trio of Daniel Zelman and brothers Glenn and Todd A. Kessler. The plot revolves around the brilliant, ruthless lawyer Patty Hewes and her protégée, recent law … Glenn Close, Rose Byrne, Tate Donovan, Ted Danson, Anastasia Griffith, Michael Nouri, Zachary Booth Added on Hulu 2022-03-29. Youtube Trailer

Pinnacle records has the perfect plan to get their sinking company back on track: a comeback concert in LA featuring Aldous Snow, a fading rockstar who has dropped off the radar in recent years. Record company intern Aaron Green is … Jonah Hill, Russell Brand, Rose Byrne, Elisabeth Moss, Tyler McKinney, Zöe Salmon, Lino Facioli Added on Amazon Prime 2023-05-06. Added on Netflix 2023-09-04. Youtube Trailer

Annie is a young, happy foster kid who's also tough enough to make her way on the streets of New York in 2014. Originally left by her parents as a baby with the promise that they'd be back for her … Quvenzhané Wallis, Jamie Foxx, Rose Byrne, Cameron Diaz, Bobby Cannavale, Adewale Akinnuoye-Agbaje, David Zayas Added on Starz 2023-02-02. Youtube Trailer

Two recently laid-off men in their 40s try to make it as interns at a successful Internet company where their managers are in their 20s. Vince Vaughn, Owen Wilson, Rose Byrne, Aasif Mandvi, Max Minghella, Josh Brener, Dylan O'Brien Added on HBO 2023-01-24. Youtube Trailer

A desk-bound CIA analyst volunteers to go undercover to infiltrate the world of a deadly arms dealer, and prevent diabolical global disaster. Melissa McCarthy, Jason Statham, Jude Law, Rose Byrne, Miranda Hart, Allison Janney, Bobby Cannavale Added on HBO 2023-09-18, leaving 2024-09-01. Youtube Trailer