The hopes and dreams of four ambitious people are shattered when their drug addictions begin spiraling out of control. A look into addiction and how it overcomes the mind and body. Ellen Burstyn, Jared Leto, Jennifer Connelly, Marlon Wayans, Christopher McDonald, Sean Gullette, Mark Margolis Added on Amazon Prime 2023-04-01. Added on HBO 2022-10-03. Youtube Trailer