Painkiller Jane is an American-Canadian science fiction and action television series based on the comic book character of the same name. Airing on the Sci Fi Channel in the US starting April 13, 2007 and Global in Canada, it starred … Kristanna Loken, Rob Stewart, Noah Danby, Stephen Lobo, Sean O. Roberts, John Reardon, Tiera Skovbye Added on Amazon Prime 2022-12-05.