Three sisters (Prue, Piper and Phoebe) reunite and unlock their powers to become the Charmed Ones, the most powerful good witches of all time, whose prophesied destiny is to protect innocent lives from evil beings such as demons and warlocks. … Holly Marie Combs, Alyssa Milano, Dorian Gregory, Brian Krause, Rose McGowan, Julian McMahon, Shannen Doherty Added on stan 2022-04-15, leaving 2024-11-21.